Saarbrücken, Germany
29.9.-1.10.2021

Cell Physics
2021

Fotos: © SFB 1027 - D. Thalla T. Faidt D. Flormann Z. Renping

Program

Schedule

Detailed Program

Conference Booklet

Schedule

Registration takes place on Wednesday (29.9.) 7:30-8:20


Wednesday(29.9.) Thursday(30.9.) Friday(1.10.)
8:20-8:30

Opening
8:30-10:30

Cytoskeleton M/A

 8:30-9:30

Membranes


9:30-11:00

Mechanobiology

 8:30-10:30

Molecular Biophysics
10:30-11:00
Coffee 		11:00-11:30
Coffee 		10:30-11:00
Coffee
11:00-13:00

Cytoskeleton A/V

13:00-13:15
 11:30-13:00

Multicellular Aggregates

11:00-13:15

13:15-14:15
Lunch (Canteen) & Poster		 13:00-14:00
Lunch (Canteen) & Poster		 13:15-14:00
Lunch (Canteen) & Poster
14:15-15:30

Molecular Biophysics

Genes
Development

14:00-15:30

Membrane Proteins

Cancer

Cell-Hydrodynamics

Mechanobiology

Fin!
15:30-16:00
Coffee
16:00-17:00

Cell compartments

17:00-18:00

Membrane Proteins

 16:00-16:30

Mechanobiology

16:30-17:30

Membrane Proteins

17:30-18:30

Cell Compartments
18:00-19:30
Posters		 18:30-20:00
Posters and Buffet
19:30
Social Dinner
(Ratskeller Saarbrücken)		 20:00
Speaker Dinner
(Restaurant Casino am Staden)		  

Detailed Program

Wednesday

Thursday

Friday

Wednesday 29.9.
Time Speaker Topic of presentation
7:30-8:20 Registration
8:20-8:30 Opening
8:30-10:30 Cytoskeleton M/A
8:30-9:00 Lukas Kapitein Matrix elasticity gradients guide neuronal polarity by controlling microtubule network mobility
9:00-9:30 Marco Fritzsche Mechanobiological control of T-cell activation
9:30-10:00 Kinneret Keren Dynamics of contracting actomyosin networks with turnover
10:00-10:30 Nir S. Gov Cellular shapes driven by curved membrane proteins that recruit the actin cytoskeleton: lamellipodia, ruffles and motility
10:30-11:00 Coffee
11:00-13:00 Cytoskeleton A/V
11:00-11:30 Matthieu Piel An active rigidity percolation transition in the actomyosin cortex drives a minimal morphogenetic and motile machinery
11:30-12:00 Paul Janmey Role of intermediate filament networks in compression stiffening of cells and protection of nuclei
12:00-12:30 John Eriksson Intermediate filaments – Dynamic structures between biomechanics and signaling
12:30-13:00 Georgia Schäfer Exogenous vimentin supplementation transiently affects early steps during HPV16 pseudovirus infection
13:00-13:15 Lumicks Company Mechanics and dynamics of cytoskeletal components and phase separated droplets studied with optical tweezers correlated to fluorescence microscopy
13:15-14:15 Lunch (Canteen) & Poster
14:15–15:30 Membranes Molecular Biophysics
14:15 - 14:30 Tanmoy Sarkar A minimal lattice model of lipid membranes with liquidordered domains ‪Ramachandra M Bhaskara‬ Molecular events during selective ER-phagy
14:30 - 14:45 Ewa Sitarska Sensing their plasma membrane curvature allows migrating cells to circumvent obstacles Massimiliano Anselmi Do the Loops in the N-SH2 Binding Cleft Truly Serve as Allosteric Switch in SHP2 Activation?
14:45 - 15:00 Nicholas Kurniawan Curvature: a dynamic regulator of cell migration mode and motility Robert A. Becker A continuous complete RNA translocation cycle by the DEAH-box helicase Prp43 in atomic detail
15:00 - 15:15 Sadegh Ghorbani Hemidesmosome-like Adhesion Mimicked through Nanopatterning of Laminin-332

Genes Development
15:15 - 15:30 Alessandra Griffo Biomechanics and architecture of unsupported and biomimetic lipid membranes: insights on geometrical constrains and lipid chemistry M. A. Ramirez Sierra Spatial-Stochastic Model of Cell Fate Decisions in Early Mouse Development
15:30-16:00 Coffee
16:00-17:00 Cell compartments
16:00-16:30 Jennifer Lippincott-Schwartz Emerging imaging technologies to study cell architecture, dynamics and function
16:30-17:00 Simon Alberti Phase separation and biomolecular condensates in biology and disease
17:00-18:00 Membrane Proteins
17:00-17:30 Bernd Fakler Fast Ca2+-transport by PMCA-Neuroplastin complexes
17:30-18:00 Edwin R. Chapman Kinetic transitions in individual recombinant exocytotic fusion pores
18:00 - 19:30 Posters
19:30 Social dinner

Thursday 30.9.
Time Speaker Topic of presentation
8:30-10:00 Membranes
8:30-9:00 Ilya Levental The lipidomic, biophysical, and functional asymmetry of the mammalian plasma membrane
9:00-9:30 Herre Jelger Risselada Facial recognition of biological lipid membranes
9:30-11:00 Mechanobiology
9:30-10:00 Viola Vogel Molecular Mechanobiology of Extracellular Matrix: Functional implications in healthy and diseased organs
10:00-10:30 Olivier Hamant Are microtubules their own mechanosensors?
10:30-11:00 Sandrine Etienne-Manneville Microtubules regulate mechanosensitive cell migration
11:00-11:30 Coffee
11:30-13:00 Multicellular Aggregates
11:30-12:00 Rosalind J. Allen Physics models for how antibiotics kill bacteria
12:00-12:30 Maria P. Alcolea A biomechanical switch regulates the transition towards homeostasis in mouse esophageal epitheium
12:30-13:00 Luis M. Escudero Biophysical approaches to explain the 3D cellular packing of epithelia
13:00-14:00 Lunch (Canteen) & Poster
14:00-15:30 Membrane Proteins Cell Hydrodynamics
14:00 - 14:15 Cornelia Monzel Elucidating Receptor Cluster Formation in CD95 Signaling via DNA Origami and Multiparametric Image Spectroscopy ‪Anil Kumar Dasanna Stochastic bond dynamics induce optimal alignment of malaria parasite
14:15 - 14:30 ‪ Priyanka Dhakane‬ Photoswtichable ICAM1 for immunological synapse studies Alexis Darras Red blood cell deformability in erythrocyte sedimentation and in vivo partitioning
14:30 - 14:45 Diana B. Peckys Quantitative Study of Heterogeneity in Membrane Protein Interaction in Cancer Cells using Liquid-Phase Electron Microscopy Mehrnaz Babaki Shape deformation of RBCs in a doublet
14:45 - 15:00

Cancer

 Athullya Baby Generation of Fluid Flows On The Skin of Xenopus Embryo
15:00 - 15:15 Hans Kubitschke Connective Tissue and Cancer Cross-Talk: Treatment Implications and Biomechanical Signature?

Mechanobiology
15:15 - 15:30 ‪ Malèke Mouelhi Long-term nuclear regulation of cancer cells under confinement Clara Ramón-Lozano Brain microvascular endothelial cell cytoskeletal reorganization in response to strain in a microvessel-on-chip
15:30-16:00 Coffee
16:00-16:30 Mechanobiology
16:00-16:30 Jan Lammerding Confined Migration Induces Heterochromatin Formation and Alters Chromatin Accessibility
16:30-17:30 Membrane Proteins
16:30-17:00 Bert L. de Groot The molecular dynamics of potassium channel permeation, selectivity and gating
17:00-17:30 Daniel A. Fletcher Mind the gap: Spatial organization and signaling at cell-cell contacts
17:30-18:30 Cell Compartments
17:30-18:00 Stefan Jakobs Focusing on the mitochondrial inner membrane with light and electron microscopy
18:00-18:30 Sarah L. Keller Yeast tune their vacuole membranes to phase separate at their growth temperatures
18:30-20:00 Posters and Buffet
20:00 Speaker dinner

Friday 1.10.
Time Speaker Topic of presentation
8:30-10:30 Molecular Biophysics
8:30-9:00 Felix Rey Class II membrane fusion proteins in hantaviruses and beyond
9:00-9:30 Jan Lipfert A Tethered Ligand Assay to Probe SARS-CoV-2:ACE2 Interactions
9:30-10:00 Oliver Daumke The mechanism of dynamin in membrane constriction - From static snapshots to a dynamic model
10:00-10:30 Sahand Jamal Rahi Optimal checkpoint strategies
10:30-11:00 Coffee
11:00-13:15 Cytoskeleton Signalling
11:00 - 11:15 Laura Schaedel Vimentin Intermediate Filaments Stabilize Dynamic Microtubules by Direct Interactions ‪Sandra Iden Lrig1 and Wnt signaling instruct partitioning of melanocytes and resident immunocytes into distinct epidermal niches
11:15 - 11:30 ‪ Zahra Mostajeran The influence of vimentin on actin dynamics and force generation in RPE1 cells Barbara Schmidt BK-channel as a fast and precise Ca2+ sensor: application to PMCA pump strength measurements
11:30 - 11:45 Raj Kumar Sadhu Modeling cellular spreading and motility on curved surfaces M.D’Urso Quantitative biophysical characterization of fibroblast activation
11:45 - 12:00 Alessandro Falconieri Mechanotransduction of axonal growth: a journey from microtubules to local phenomena Cas van der Putten Understanding cell behavior in complex multi-cue environments
12:00 - 12:15 Dmitry A. Fedosov Sculpting vesicles with active particles

Multicellular Aggregates

12:15 - 12:30 ‪ K. Kaub Differential microrheological properties of actin isoforms Erik Maikranz Theoretical modelling of competitive microbial range expansion with heterogeneous mechanical interactions
12:30 - 12:45 ‪ Peter Nietmann Nonequilibrium mechanics of cross-linked actomyosin networks probed with microrheological techniques Adam Wysocki Collective Search Strategies
12:45 - 13:00 ‪ Andreas Weber A-to-I RNA editing of Filamin A (FLNA) regulates cellular adhesion, migration and mechanical properties Alice Abend Adhesion dynamics and organization of neurons and glial cells on nanocolumnar TiN substrates
13:00 - 13:15 ‪Cécile Jebane Premature senescence by lamin A/C alterations correlates to changes in cell viscoelastic behavior Sylvain Monnier Probing cell volume in compressed tissues with Brillouin light scattering
13:15-14:00 Lunch (Canteen)& Poster
Fin!

List of contributed talks

List of posters



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Saarbrücken, Germany, 29.9.-1.10.2021
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