Saarbrücken, Germany
9.-11.10.2019

Cell Physics
2019

Fotos: © SFB 1027 - R. Zhao Z. Mostajeran L. Kainka T. Fredrich

Schedule

Detailed Program

Conference Booklet

Schedule

Registration takes place on Wednesday (9.10.) 7:30-8:20


Wednesday(9.10.) Thursday(10.10.) Friday(11.10.)
8:20-8:30

Opening

8:30-10:30

Actin I

8:30-10:30

Tissues / Cancer

8:30-10:30

Actin II

10:30-11:00
Coffee
11:00-13:00

Immune Cells

11:00-12:30

Cell State

Membrane proteins

11:00-13:00

13:00-14:00
Lunch Buffet & Poster
12:30-13:30
Lunch Buffet & Poster
13:00-14:00
Lunch Buffet & Poster

14:00-15:00

Cell Mechanics I

13:30-15:00

14:00-14:45

Membrane Channels

15:00-15:20
Coffee
14:45 - 15:00
Coffee

15:20-16:20

Cell Mechanics II

Intracellular Transport

15:20-16:20

15:00-17:00

Microtubules

16:30-17:30

Cell nucleus

16:30-17:30

Adhesion

17:00

Fin

17:30-19:00
Posters & Snacks
19:00
Social dinner(Aula)
19:00
Social dinner(Tent)
 

Detailed Program

Wednesday

Thursday

Friday

Wednesday 9.10.

Time Speaker Topic of presentation
7:30-8:20 Registration
8:20-8:30 Opening
8:30-10:30 Actin I
8:30-9:00 Gijsje H. Koenderink From mechanical resilience to active materialpropertiesin biopolymer networks
9:00-9:30 Martin Lenz Elasticity from entanglements in branched actin
9:30-10:00 Andreas Janshoff Viscoelastic properties of cells and cellular cortices
10:00-10:30 Anne Bernheim-Groswasser Spontaneous shape transitions of active contractile sheets
10:30-11:00 Coffee
11:00-13:00 Immune Cells
11:00-11:30 Kheya Sengupta Morphodynamics and mechanosensitivity of spreading T cells
11:30-12:00 Olivier Theodoly Directed migration of lymphocytes by integrins
12:00-12:30 Pawel Paszek
12:30-13:00 Ana-Maria Lennon-Duménil Impact of Mechanical Stress on the Immune-surveillance function of dendritic cells
13:00-14:00 Lunch Buffet & Poster
14:00–15:00 Cell Mechanics I Nano Probes
14:00 - 14:15 Ayelet Lesman Mechanical interaction between cells in fibrous environments Cornelia Monzel Subcellular Transfer of Nanoparticles and Targeting of Organelles oscillations
14:15 - 14:30 Hans V. Oosterwyck Sprouting angiogenesis relies on tip cell pulling forces Alessandro Falconieri Mechanotransduction of axonal growth: novel perspectives in mechanobiology field
14:30 - 14:45 Baeckkyoung Sung Dynamics of immune cell morphology and motility on a topographical surface with controlled elasticity Mitchell Han Optoregulated force application to individual cellular receptors using molecular motors
14:45 - 15:00 Satoru Kidoaki Exercising mesenchymal stem cells through nomadic culture on heterogeneous field of matrix elasticity Yesaswini Komaragiri Role of oxidative stress on the cell mechanical properties of suspended and adherent cells
15:00-15:20 Coffee
15:20-16:20 Cell Mechanics II Intracellular Transport
15:20-15:35 Fern J. Armistead Mechanical phenotyping of single cells using shear and inertial microfluidics Naruemon Rueangkham Intracellular transport by molecular motors: the effect of number of binding sites
15:35-15:50 Bob Fregin Dynamic real-time deformability cytometry: High-throughput single cell rheology in complex samples M. Reza Shaebani Dynamics, correlations, and search optimization in active processes with distinct motility states
15:50-16:05 Christian Dietz Nanomechanical sub-surface mapping of living biological cells by force microscopy Matthieu Mangeat The narrow escape problem in a circular domain with radial piecewise constant diffusivity
16:05-16:20     Saptarshi Chatterjee Microtubule search-and-capture mechanism orchestrates MTOC clustering and nuclear division via proper spindle positioning in yeast
16:30-17:30 Cell nucleus
16:30-17:00 Rhoda J. Hawkins Force exertion on the cell nucleus
17:00-17:30 Dennis E. Discher Nuclear Rupture at high curvature & high ratescauses defects in DNA repair, affecting cell cycle, differentiation, &genome variation
17:30 - 19:00 Posters & Snacks
19:00 Social dinner(Aula)

Thursday 10.10.

Time Speaker Topic of presentation
8:30-10:30 Tissues / Cancer
8:30-9:00 Peter Friedl Jamming transitions of cancer cells during tissue invasion
9:00-9:30 Guillaume Charras Dissecting the intercellular forces shaping tissues
9:30-10:00 Timo Betz Walk my way: Collective migration in development and cancer
10:00-10:30 Dave Thirumalai Cell growth rate dictates the onset of glass to fluid-like transition and long time super-diffusion in an evolving cell colony
10:30-11:00 Coffee
11:00-11:30 Cell State
11:00-11:30 Sui Huang Dynamics of cell state transitions – theory & single-cell transcriptomics
11:30-12:30 Membrane proteins
11:30-12:00 Jochen Hub Molecular simulations of protein-membrane interactions during membrane fusion
12:00-12:30 Gerhard Hummer Remodeling and destruction of biological membranes
12:30-13:30 Lunch Buffet & Poster
13.30 – 15.00 Cancer Actomyosin Networks
13:30-13:45 Tobias Büscher Tissue Competition: Coexistence and Tumor Heterogeneity Clément Campillo Morphology and mechanics of membrane nanotubes interacting with reconstituted actin networks
13:45-14:00 Thierry Fredrich Fine- grained simulation of the microenvironment of vascularized tumors Mohammad Abu Hamed A simple model of Keratocyte interface dynamics
14:00-14:15 Jakob Rosenbauer Multiscale Modeling of Tumor Development Daniel Amadeus Dominic Flormann Structural analysis of the actin cortex and its correlation to cell mechanics in adhered and suspended states
14:15-14:30 Aldo Leal-Egana Confining cancer cells in 3D tumor-like microcapsules: A new strategy to induce tumor heterogeneity in vitro, and to enhance extravasation capabilities in vivo Indra Navina Dahmke Association of signaling active ErbB2 homodimers with actin-rich membrane structures of cancer cells revealed by liquid phase electron microscopy
14:30-14:45 Audrey Prunet Soft cell confiner development to decipher the impact of mechanical stimuli on cancer cells Gerrit Vliegenthart Filamentous Active Matter: Band Formation, Bending, Buckling, and Defects
14:45-15:00 Andreas Weber Does estrogen receptor drug binding influence breast cancer cell viscoelasticity? Karol Makuch Stokes' law in complex liquids and inside cell cytoplasm
15:00-15:20 Coffee
15:20-16:20 Adhesion Intermediate Filaments
15:20-15:35 Diego Vargas Effect of substrate stiffness on balance of active cell-cell and cell-ECM forces studied through a computational model of a deformable cell pair Anna V. Schepers Tuning the mechanics of single intermediate filaments
15:35-15:50 Christian Spengler Single-Cell Force Spectroscopy to Study Bacterial Adhesion: Fundamental Mechanisms and Effect of Substrate Nano-Topography Franziska Lautenschläger Vimentin provides the mechanical resilience required for amoeboid migration and protection of the nucleus
15:50-16:05 Sadegh Ghorbani KRestricting desmosomal assembly in interfollicular stem cells (IFSCs) via desmosomal protein nanopatterns Julia Kraxner Recovery Behavior of Single Vimentin Filaments
16:05-16:20     Charlotta Lorenz Lateral Subunit Coupling Determines Intermediate Filament Mechanics
16:30-17:30 Adhesion
16:30-17:00 Ana-Sunčana Smith Physical effects catalyzing cell adhesion: from mimetic systems to tissues
17:00-17:30 Hermann E. Gaub Molecular Mechanisms of Extreme Mechanostability in Microbial Adhesion
17:30 - 19:00 Posters & Snacks
19:00 Social dinner(Tent)

Friday 11.10.

Time Speaker Topic of presentation
8:30-10:30 Actin II
8:30-9:00 Patricia Bassereau Linkers at the membrane-cortical actin interface: only linkers?
9:00-9:30 Claudia Steinem The architecture and mechanics of ezrin-linked minimal actin cortices
9:30-10:00 Laurent Blanchoin Reconstitution of the dynamic steady state of actin networks
10:00-10:30 Carsten Janke The tubulin code – a mechanism to control microtubule properties
10:30-11:00 Coffee
11:00-13:00 Tissues & Morphogenesis Membranes
11:00-11:15     Luca Barberi ESCRT-III helical polymers deform membranes into helical tubes
11:15-11:30 Gabriele Lubatti Cell competition in mouse embryo A. E. Hafner Physical modelling of ESCRT-III mediated cell division in archaea
11:30-11:45 Chii Jou Chan A bottom-up approach to study the interplay between signaling and mechanics in early mammalian embryogenesis Oded Farago Interplay between membrane elasticity and active cytoskeleton forces regulates the aggregation dynamics of the immunological synapse
11:45-12:00 Pau Guillamat Bassedas Integer topological defects steer cell flows during tissue morphogenesis Christian Bächer Blood platelet formation - a biological Rayleigh-Plateau instability
12:00-12:15 Carles Blanch-Mercader Onset of 3D tissue morphogenesis near integer topological defects Sebastian Kruss Entropic chromatin swelling drives complex cellular behavior
12:15-12:30 Guanming Zhang Collective behaviour of epithelial cells under different coordinated dynamics of cell polarisation Ewa Sitarska Towards understanding the role of BAR domain proteins in membrane tension sensing
12:30-12:45 Nicholas A. Kurniawan Entropic origins of substrate-guided cell morphology and alignment Joel C. Forster Relating Surface Structure to Function in Cell Membrane Penetrating Nanoparticles
12:45-13:00     Hendrik Hähl Hydrophobins: Model proteins and building blocks for lipid-free membranes and vesicles
13:00-14:00 Lunch Buffet & Poster
14:00-14:45 Bacteria Membrane Channels
14:00-14:15 Daniel Pearce Geometry and mechanics of growing bacterial suspensions Dalia Alansary Biochemical and electrophysiological approaches for studying the stoichiometry of ORAI channels
14:15-14:30 Javad Najafi Flagellar number governs bacterial spreading and transport efficiency Miloš Ivanović Interpretation of SAXS data using MD simulations: Detergent micelles and ion cloud of charged proteins
14:30-14:45 Shrikrishnan Sankaran Bacterial confinement in hydrogels to develop living therapeutic materials S. G. Romanova Stilbene derivative as a photosensitive compound to control the excitability of neonatal rat cardiomyocytes
14:45-15:00 Coffee
15:00-17:00 Microtubules
15:00-15:30 Tatyana Svitkina How microtubules induce local membrane protrusion
15:30-16:00 Alexander D. Bershadsky Crosstalk between myosin IIA filaments, integrinmediated cell-matrix adhesions, and microtubules
16:00-16:30 Rudolf Merkel Cyclic Stretch is a Potent Cue for Animal Cells
16:30-17:00 Iva Tolić Torques and forces in the mitotic spindle
17:00 Fin

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